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doi: 10.3389/fnut.2025.1693167 Received 26 August 2025 Accepted 03 November 2025 Published 28 November 2025 Volume 12 - 2025 Edited by Giacomo Di Matteo, Sapienza University of Rome, Italy Reviewed by Zhili Liang, Guangdong Food and Drug Vocational College, China Emmanuel Kingsley Darkwah, Missouri University of Science and Technology, United States Updates Copyright 2025 Semchyshyn
Selective GHSR activation
In one study, patients regained about two-thirds of the weight they had lost just one year after stopping semaglutide treatment, and their cardiometabolic risk markers (blood sugar, cholesterol, etc.) reverted toward baseline (source)
It works best in conjunction with a healthy lifestyle
The calculator is a verification tool rather than a substitute for understanding the arithmetic
